| Fecha | Hora | Casa | Fuera | Fase | Edición | ||||
|---|---|---|---|---|---|---|---|---|---|
| 2021-10-06 | LDU Portoviejo |  | 1-0 |  | Chacaritas SC | J35 | |||
| 2021-09-22 | 17:30 | LDU Portoviejo | | 3-3 |  | Atlético Santo Domingo | J33 | ||
| 2021-09-08 | 20:00 | LDU Portoviejo | | 0-1 |  | Independiente Juniors | J31 | ||
| 2021-08-25 | LDU Portoviejo | | 0-0 |  | América Quito | J29 | |||
| 2021-08-04 | LDU Portoviejo | | 1-1 |  | Gualaceo SC | J26 |
