| Pts | P | V | E | D | GM | GR | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 |  | FBC Melgar | 12 | 6 | 4 | 0 | 2 | 10 | 6 |
| 2 |  | Racing Club | 12 | 6 | 4 | 0 | 2 | 7 | 5 |
| 3 |  | Cuiabá | 6 | 6 | 2 | 0 | 4 | 7 | 10 |
| 4 |  | River Plate | 6 | 6 | 2 | 0 | 4 | 5 | 8 |
| 2022/04/08 | Grp.B | River Plate | | 0-1 | | Racing Club | ||||
| 2022/04/08 | Grp.B | Cuiabá | | 2-0 | | FBC Melgar | ||||
| 2022/04/14 | Grp.B | FBC Melgar | | 2-0 | | River Plate | ||||
| 2022/04/14 | Grp.B | Racing Club | | 2-0 | | Cuiabá | ||||
| 2022/04/28 | Grp.B | Cuiabá | | 1-2 | | River Plate | ||||
| 2022/04/28 | Grp.B | FBC Melgar | | 3-1 | | Racing Club | ||||
| 2022/05/04 | Grp.B | Cuiabá | | 1-2 | | Racing Club | ||||
| 2022/05/04 | Grp.B | River Plate | | 1-2 | | FBC Melgar | ||||
| 2022/05/19 | Grp.B | River Plate | | 1-2 | | Cuiabá | ||||
| 2022/05/19 | Grp.B | Racing Club | | 1-0 | | FBC Melgar | ||||
| 2022/05/27 | Grp.B | FBC Melgar | | 3-1 | | Cuiabá | ||||
| 2022/05/27 | Grp.B | Racing Club | | 0-1 | | River Plate |
 | Clasificación |
| 2 |
|
Stiven Mendoza Ceará | 6 G |
| 3 |
|
Miguel Borja Junior Barranquilla | 5 G |
| 3 |
|
Luciano São Paulo | 5 G |
| 3 |
|
Lautaro Díaz Independiente del Valle | 5 G |
| 2 |
|
Júnior Sornoza Independiente del Valle | 4 AST: |
| 3 |
|
Richard Salinas Guaireña FC | 3 AST: |
| 3 |
|
Diego Churín Atlético Goianiense | 3 AST: |
| 3 |
|
Taison Internacional | 3 AST: |
