| 2022/07/03 | Eding Sport |  | 1-1 (1-2 pen.) |  | Cotonsport |
| 2022/07/03 | Canon Yaoundé |  | 3-2 |  | Astres |
| 2022/07/01 | Yafoot |  | 0-1 |  | Panthère FC |
| P | GM | GR | Pts | |||
|---|---|---|---|---|---|---|
| 1 | | Astres | 24 | 36 | 18 | 51 |
| 2 | | Canon Yaoundé | 24 | 34 | 20 | 45 |
| 3 |  | Colombe Sportive | 24 | 47 | 28 | 40 |
| 4 |  | Union Douala | 24 | 32 | 26 | 39 |
| 5 |  | Feutcheu FC | 24 | 29 | 27 | 36 |
| 6 |  | APEJES Mfou | 24 | 27 | 30 | 35 |
| 7 |  | Stade Renard | 24 | 32 | 27 | 34 |
| 8 |  | AS Fortuna | 24 | 46 | 44 | 32 |
| 9 |  | YOSA FC | 24 | 23 | 27 | 29 |
| 10 |  | Fauve Azur FC | 24 | 37 | 42 | 28 |
| 11 | | Panthère FC | 24 | 28 | 36 | 27 |
| 12 |  | Tonnerre Yaoundé | 24 | 17 | 43 | 17 |
| 13 |  | Racing FC Bafoussam | 24 | 20 | 40 | 13 |
| P | GM | GR | Pts | |||
|---|---|---|---|---|---|---|
| 1 | | Eding Sport | 22 | 29 | 12 | 47 |
| 2 | | Cotonsport | 22 | 37 | 14 | 42 |
| 3 |  | FC Bamenda | 22 | 26 | 22 | 33 |
| 4 |  | Fovu | 22 | 20 | 19 | 33 |
| 5 |  | Bamboutos | 22 | 24 | 21 | 32 |
| 6 |  | UMS de Loum | 22 | 24 | 19 | 31 |
| 7 |  | Avion Academy | 22 | 21 | 21 | 27 |
| 8 |  | Renaissance | 22 | 21 | 31 | 23 |
| 9 |  | Dragon Club | 22 | 25 | 36 | 23 |
| 10 | | Yafoot | 22 | 21 | 25 | 22 |
| 11 |  | New Star Douala | 22 | 17 | 29 | 21 |
| 12 |  | OFTA | 22 | 17 | 33 | 19 |
 | Play-off campeón |
| Descenso |
