| Pts | P | V | E | D | GM | GR | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Benfica | 15 | 6 | 5 | 0 | 1 | 14 | 4 |
| 2 |  | Dynamo Kyiv | 13 | 6 | 4 | 1 | 1 | 14 | 3 |
| 3 |  | Barcelona | 4 | 6 | 1 | 1 | 4 | 5 | 14 |
| 4 |  | Bayern München | 3 | 6 | 1 | 0 | 5 | 4 | 16 |
| 2021/09/14 | Grp.E | Dynamo Kyiv | | 4-0 | | Benfica | ||||
| 2021/09/14 | Grp.E | Barcelona | | 2-0 | | Bayern München | ||||
| 2021/09/29 | Grp.E | Bayern München | | 0-4 | | Dynamo Kyiv | ||||
| 2021/09/29 | Grp.E | Benfica | | 4-0 | | Barcelona | ||||
| 2021/10/20 | Grp.E | Barcelona | | 0-0 | | Dynamo Kyiv | ||||
| 2021/10/20 | Grp.E | Benfica | | 4-0 | | Bayern München | ||||
| 2021/11/02 | Grp.E | Dynamo Kyiv | | 4-1 | | Barcelona | ||||
| 2021/11/02 | Grp.E | Bayern München | | 0-2 | | Benfica | ||||
| 2021/11/23 | Grp.E | Dynamo Kyiv | | 2-1 | | Bayern München | ||||
| 2021/11/23 | Grp.E | Barcelona | | 0-3 | | Benfica | ||||
| 2021/12/08 | Grp.E | Benfica | | 1-0 | | Dynamo Kyiv | ||||
| 2021/12/08 | Grp.E | Bayern München | | 3-2 | | Barcelona |
 | Clasificación |
| Play-off clasificación |
| 1 |
|
Aral Simsir Midtjylland | 7 G |
| 3 |
|
Filip Cuic Hajduk Split | 6 G |
| 3 |
|
Roko Simic Red Bull Salzburg | 6 G |
| 3 |
|
Jamie Bynoe-Gittens Borussia Dortmund | 6 G |
