| Pts | P | V | E | D | GM | GR | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Sporting | 11 | 6 | 3 | 2 | 1 | 11 | 8 |
| 2 |  | Borussia Dortmund | 10 | 6 | 3 | 1 | 2 | 16 | 9 |
| 3 |  | Ajax | 10 | 6 | 3 | 1 | 2 | 9 | 10 |
| 4 |  | Besiktas | 3 | 6 | 1 | 0 | 5 | 8 | 17 |
| 2021/09/15 | Grp.C | Sporting | | 1-1 | | Ajax | ||||
| 2021/09/15 | Grp.C | Besiktas | | 2-3 | | Borussia Dortmund | ||||
| 2021/09/28 | Grp.C | Ajax | | 3-1 | | Besiktas | ||||
| 2021/09/28 | Grp.C | Borussia Dortmund | | 0-0 | | Sporting | ||||
| 2021/10/19 | Grp.C | Besiktas | | 1-3 | | Sporting | ||||
| 2021/10/19 | Grp.C | Ajax | | 1-5 | | Borussia Dortmund | ||||
| 2021/11/03 | Grp.C | Borussia Dortmund | | 0-1 | | Ajax | ||||
| 2021/11/03 | Grp.C | Sporting | | 1-2 | | Besiktas | ||||
| 2021/11/24 | Grp.C | Besiktas | | 0-1 | | Ajax | ||||
| 2021/11/24 | Grp.C | Sporting | | 3-2 | | Borussia Dortmund | ||||
| 2021/12/07 | Grp.C | Borussia Dortmund | | 6-2 | | Besiktas | ||||
| 2021/12/07 | Grp.C | Ajax | | 2-3 | | Sporting |
 | Clasificación |
| Play-off clasificación |
| 1 |
|
Aral Simsir Midtjylland | 7 G |
| 3 |
|
Filip Cuic Hajduk Split | 6 G |
| 3 |
|
Roko Simic Red Bull Salzburg | 6 G |
| 3 |
|
Jamie Bynoe-Gittens Borussia Dortmund | 6 G |
