| Pts | P | V | E | D | GM | GR | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Liverpool | 11 | 6 | 3 | 2 | 1 | 9 | 4 |
| 2 |  | Atlético Madrid | 10 | 6 | 3 | 1 | 2 | 9 | 6 |
| 3 |  | FC Porto | 10 | 6 | 3 | 1 | 2 | 8 | 9 |
| 4 |  | Milan | 2 | 6 | 0 | 2 | 4 | 3 | 10 |
| 2021/09/15 | Grp.B | Atlético de Madrid | | 1-2 | | FC Porto | ||||
| 2021/09/15 | Grp.B | Liverpool | | 1-0 | | Milan | ||||
| 2021/09/28 | Grp.B | Milan | | 1-1 | | Atlético de Madrid | ||||
| 2021/09/28 | Grp.B | FC Porto | | 1-1 | | Liverpool | ||||
| 2021/10/19 | Grp.B | FC Porto | | 3-1 | | Milan | ||||
| 2021/10/19 | Grp.B | Atlético de Madrid | | 2-0 | | Liverpool | ||||
| 2021/11/03 | Grp.B | Milan | | 0-1 | | FC Porto | ||||
| 2021/11/03 | Grp.B | Liverpool | | 2-0 | | Atlético de Madrid | ||||
| 2021/11/24 | Grp.B | Liverpool | | 4-0 | | FC Porto | ||||
| 2021/11/24 | Grp.B | Atlético de Madrid | | 3-0 | | Milan | ||||
| 2021/12/07 | Grp.B | Milan | | 1-1 | | Liverpool | ||||
| 2021/12/07 | Grp.B | FC Porto | | 1-2 | | Atlético de Madrid |
 | Clasificación |
| Play-off clasificación |
| 1 |
|
Aral Simsir Midtjylland | 7 G |
| 3 |
|
Filip Cuic Hajduk Split | 6 G |
| 3 |
|
Roko Simic Red Bull Salzburg | 6 G |
| 3 |
|
Jamie Bynoe-Gittens Borussia Dortmund | 6 G |
